Amiloride hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0890

Na+ channel blocker; also I2 imidazoline ligand
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Key Product Details

Description

Na+ channel blocker; also I2 imidazoline ligand

View all Voltage-gated Sodium Channel Blockers »

Product Description

Amiloride hydrochloride is a Na+ channel blocker. Defines the I2A-amiloride sensitive and I2B-amiloride insensitive imidazoline binding Blocks TRPP3, acid sensing- (ASIC) and mechanogated membrane-ion channels, as well as the Na+/H+ exchanger. Also inhibits urokinase-type plasminogen activator (uPA); has no effect on tissue-type plasminogen activator.

Product Specifications

Molecular Weight

266.09

Formula

C6H8ClN7O.HCl

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide hydrochloride

CAS Number

2016-88-8

PubChem ID

16230

InChI Key

ACHKKGDWZVCSNH-UHFFFAOYSA-N

SMILES

Cl.NC(=N)NC(=O)C1=NC(Cl)=C(N)N=C1N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 1.33 5 with gentle warming
DMSO 26.61 100

Preparing Stock Solutions for Amiloride hydrochloride

The following data is based on the product molecular weight 266.09

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.76 mL 18.79 mL 37.58 mL
5 mM 0.75 mL 3.76 mL 7.52 mL
10 mM 0.38 mL 1.88 mL 3.76 mL
50 mM 0.08 mL 0.38 mL 0.75 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Amiloride hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Amiloride hydrochloride

For research use only

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