451 results for "MDM2/HDM2" in Products
MDM2/HDM2 Products
MDM2 is a key regulator of p53 tumor suppressor protein activity and stability. MDM2 binds to and inhibits the transactivation domain of p53. In addition, MDM2 controls p53 stability by functioning as its E3 ligase in ubiquitination and by shuttling p53 from the nucleus to the cytoplasm for subsequent degradation. The importance of the p53/MDM2 relationship is underscored by the existence of an autoregulatory feedback loop whereby activated p53 transcriptionally upregulates the expression of its own inhibitor, MDM2.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC |
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| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #MDM2/7190R |
| Applications: | IHC |
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| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #MDM2/7190R |
| Applications: | IHC |
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| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #MDM2/7942 |
| Applications: | IHC |
Conjugate
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| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #MDM2/7942 |
| Applications: | IHC |
Conjugate
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| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #MDM2/8221 |
| Applications: | IHC |
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| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #rMDM2/9214 |
| Applications: | IHC |
![MDM2/HDM2 Antibody (rMDM2/9214) - Azide and BSA Free Immunohistochemistry-Paraffin: MDM2/HDM2 Antibody (rMDM2/9214) - Azide and BSA Free [NBP3-24198] -](https://resources.bio-techne.com/images/products/nbp3-24198_mouse-mdm2-hdm2-mab-rmdm2-9214-azide-and-bsa-free-24120257592892.jpg "Immunohistochemistry-Paraffin: MDM2/HDM2 Antibody (rMDM2/9214) - Azide and BSA Free [NBP3-24198] -")
Conjugate
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| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #rMDM2/9214 |
| Applications: | IHC |
![MDM2/HDM2 Antibody (rMDM2/9214) Immunohistochemistry-Paraffin: MDM2/HDM2 Antibody (rMDM2/9214) [NBP3-23760] -](https://resources.bio-techne.com/images/products/nbp3-23760_mouse-mdm2-hdm2-mab-rmdm2-9214-2412025872365.jpg "Immunohistochemistry-Paraffin: MDM2/HDM2 Antibody (rMDM2/9214) [NBP3-23760] -")
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| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #MDM2/7189R |
| Applications: | IHC |
Conjugate
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| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #MDM2/7189R |
| Applications: | IHC |
Conjugate
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| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #MDM2/8221 |
| Applications: | IHC |
Conjugate
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| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #MDM2/7061R |
| Applications: | ELISA |
Conjugate
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| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #MDM2/7061R |
| Applications: | ELISA |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
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| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #MDM2/7190R |
| Applications: | IHC |
Conjugate
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| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #MDM2/7189R |
| Applications: | IHC |
Conjugate
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| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #MDM2/7061R |
| Applications: | ELISA |
Conjugate
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| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #MDM2/7189R |
| Applications: | IHC |
Conjugate
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| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #MDM2/7190R |
| Applications: | IHC |
Conjugate
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| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #MDM2/7942 |
| Applications: | IHC |
Conjugate
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| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #MDM2/7061R |
| Applications: | ELISA |
Conjugate
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| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #rMDM2/9214 |
| Applications: | IHC |
Conjugate
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| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #MDM2/7942 |
| Applications: | IHC |
![MDM2/HDM2 Antibody (MDM2/7942) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-21087cl1_mouse-mdm2-hdm2-mab-mdm2-7942-corafluor-1-810202510462624.png "Product Feature: CoraFluor Probes for TR-FRET")
Conjugate
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| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #MDM2/8221 |
| Applications: | IHC |
![MDM2/HDM2 Antibody (MDM2/8221) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-21091cl1_mouse-mdm2-hdm2-mab-mdm2-8221-corafluor-1-810202510443516.png "Product Feature: CoraFluor Probes for TR-FRET")
Conjugate
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| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #MDM2/7189R |
| Applications: | IHC |
![MDM2/HDM2 Antibody (MDM2/7189R) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-21097cl1_rabbit-mdm2-hdm2-mab-mdm2-7189r-corafluor-1-12920251591219.png "Product Feature: CoraFluor Probes for TR-FRET")
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