LPAR1/LPA1/EDG-2: Small Molecules and Peptides
EDG molecules are G protein-coupled receptors that bind plasma lysophospholipids. The EDG family consists of two subfamilies; the S1P (sphingosine-1-phosphate) subfamily consisting of EDG-1, 3, 5, 6, and 8, and the LPA (lysophosphatidic acid) subfamily that contains EDG-2, 4 and 7. Each receptor is the product of a distinct gene. The S1P family regulates essential cellular processes such as proliferation, migration, cytoskeletal organization, and differentiation.
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2 results for "LPAR1/LPA1/EDG-2 Small Molecules and Peptides" in Products
2 results for "LPAR1/LPA1/EDG-2 Small Molecules and Peptides" in Products
LPAR1/LPA1/EDG-2: Small Molecules and Peptides
EDG molecules are G protein-coupled receptors that bind plasma lysophospholipids. The EDG family consists of two subfamilies; the S1P (sphingosine-1-phosphate) subfamily consisting of EDG-1, 3, 5, 6, and 8, and the LPA (lysophosphatidic acid) subfamily that contains EDG-2, 4 and 7. Each receptor is the product of a distinct gene. The S1P family regulates essential cellular processes such as proliferation, migration, cytoskeletal organization, and differentiation.
Products:
Endogenous agonist of LPA1 and LPA2
| Chemical Name: | 1-O-9Z-Octadecenoyl-sn-glyceryl-3-phosphoric acid sodium salt |
Potent LPA1 antagonist
| Chemical Name: | 1-[4'-[4-Methyl-5-[[[(1R)-1-phenylethoxy]carbonylamino]-1H-1,2,3-triazol-1-yl][1,1'-biphenyl]-4-yl]cyclopropanecarboxylic acid |
| Purity: | ≥98% (HPLC) |