LIGHT/TNFSF14 Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
Products:
353 results for "LIGHT/TNFSF14" in Products
353 results for "LIGHT/TNFSF14" in Products
LIGHT/TNFSF14 Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
Products:
| Applications: | Ctrl, Simple Plex |
| Source: | NS0 |
| Accession #: | O43557 |
| Applications: | BA |
| Sensitivity: | 16.5 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva) |
| Source: | NS0 |
| Accession #: | Q9QYH9 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA, IHC, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #885310 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2323C |
| Applications: | Flow, CyTOF-ready, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #261639 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #261639 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #261639 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #906909 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA, IHC, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115515R |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #885310 |
| Applications: | Flow |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #261639 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #261639 |
| Applications: | WB |