10 results for "KOR Small Molecules and Peptides" in Products
KOR Small Molecules and Peptides
Kappa Opioid Receptor (KOR) is a 45 kDa 7TM opioid receptor that is primarily expressed in the central nervous system and peripheral visceral pain sensory nerves. Following ligation by dynorphin peptides, KOR signaling induces analgesia, dysphoria, diuresis, and increased feeding desire. KOR also exerts neuroprotective and anti-inflammatory effects. Human KOR shares 94% amino acid sequence identity with mouse and rat KOR.
Selective and irreversible κ antagonist
Selective κ agonist
Activator of κ-opioid DREADD (KORD)
Selective κ agonist; less active enantiomer of (±)-U-50488 (Cat. No. 0495)
Selective κ agonist; more active enantiomer of (±)-U-50488 (Cat. No. 0495)
Opioid receptor antagonist
κ agonist, acts peripherally
Subtype-selective κ agonist
Endogenous κ agonist
Selective and irreversible κ antagonist