Klotho beta Products
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
204 results for "Klotho beta" in Products
204 results for "Klotho beta" in Products
Klotho beta Products
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
| Source: | NS0 |
| Accession #: | Q86Z14 |
| Applications: | BA |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Source: | NS0 |
| Accession #: | NP_112457 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | EHH53620.1 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1025C |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1025C |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1025C |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1025C |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1025C |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #8# |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #RG7992 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #NGM313 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #NGM313 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #NGM313 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #RG7992 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #RG7992 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #885935 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #885935 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #885935 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1025C |
| Applications: | ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |