Klotho beta Antibody (885935) [Allophycocyanin]
Novus Biologicals, part of Bio-Techne | Catalog # FAB5889A
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # 885935
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Klotho beta
Phe53-Leu997
Accession # Q86Z14
Phe53-Leu997
Accession # Q86Z14
Specificity
Detects human Klotho beta in direct ELISA and Western blots.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Applications for Klotho beta Antibody (885935) [Allophycocyanin]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Klotho beta
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
Alternate Names
KLB
Gene Symbol
KLB
Additional Klotho beta Products
Product Documents for Klotho beta Antibody (885935) [Allophycocyanin]
Product Specific Notices for Klotho beta Antibody (885935) [Allophycocyanin]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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