Klotho beta: Proteins and Enzymes
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
3 results for "Klotho beta Proteins and Enzymes" in Products
3 results for "Klotho beta Proteins and Enzymes" in Products
Klotho beta: Proteins and Enzymes
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
| Source: | NS0 |
| Accession #: | Q86Z14 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | NP_112457 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | EHH53620.1 |
| Applications: | BA |
