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100 results for "IRS2" in Products

IRS2 Products

Insulin receptor substrates (IRS), the major intracellular substrates of the insulin receptor (IR), are adaptor proteins that transduce signals from the IR to downstream effectors that are important for the biological effect of insulin (1-2). After insulin stimulation, IRS proteins are rapidly phosphorylated on multiple tyrosine residues. Once phosphorylated, IRS proteins bind and activate Grb-2, SHP2 and the PI3-K p85 subunit (2-3). Sequences of IRS-2 and IRS-1 reveal a highly conserved amino ...

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Recombinant Monoclonal Antibody

Catalog #: AF6347AFP680
Catalog #: AF6347AFP488
Catalog #: AF6347AFP555
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