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IL-29/IFN-lambda 1 Products
Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.
8 results for "IL-29/IFN-lambda 1" in Products
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IL-29/IFN-lambda 1 Products
Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.
8 results for "IL-29/IFN-lambda 1" in Products
(NS0-expressed)
| Source : | NS0 |
| Accession # : | Q8IU54 |
| Applications : | Bioactivity |
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #247801 |
| Applications : | Block/Neutralize, ELISA Capture |
_MAB15981_Block_Neutralize_9030.jpg "IL‑29/IFN‑ lambda 1 Inhibition of EMCV‑induced Cytopathy and Neutralization by Human IL‑29/IFN‑ lambda 1 Antibody.")
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Western Blot |
E. coli-expressed
| Source : | E. coli |
| Accession # : | Q8IU54.1 |
| Applications : | Bioactivity |
