9 results for "IL-15R alpha" in Products
IL-15R alpha Products
IL-15Ra (Interleukin 15 Receptor alpha), also known as CD215, is a transmembrane glycoprotein that plays an important role in NK and CD8+ memory T cell homeostasis and activation. It transmits IL-15 induced signals and additionally interacts with a complex of IL-2Rβ and the common gamma chain (γc) which are also subunits of the IL-2 receptor complex. In transpresentation, IL-15/IL-15Ra complexes are expressed on the surface of one cell and interact with complexes of IL-2Rb/gc on adjacent cells. IL-15/IL-15Ra complexes can transmit reverse signaling that promotes adhesion and activation of the IL-15/IL-15Ra expressing cells. Shed soluble forms of IL-15Ra retain the ability to bind tightly to IL-15 and can inhibit IL-15 bioactivity.
| Reactivity: | Mouse |
| Details: | Rat IgG2B Monoclonal Clone #888220 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #1020456 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2639B |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #151307 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #JM7A4 |
| Applications: | WB, Flow, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready, +2 More |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready, B/N |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0103-6C38 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA |