Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Dual RNAscope ISH-IHC, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Neutralization, Western Blot

Label

Janelia Fluor 646

Antibody Source

Polyclonal Goat IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IL-15R alpha Antibodies »

Product Specifications

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human
IL‑15 R alpha
Ile31-Thr172
Accession # EAW86418

Specificity

Detects human IL-15 R alpha in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant humanIL‑2 R gamma is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for IL-15R alpha Antibody [Janelia Fluor® 646]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Dual RNAscope ISH-IHC

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Neutralization

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-15R alpha

IL15RA is a gene that codes for a protein that is a high-affinity receptor for interleukin-15, and can signal in both cis and trans to neighboring IL2RG-expressing cells, but the expression of different isoforms may interfere with this signal transduction, as isoforms 5-8 do not bind to IL15. The isoforms are all highly expressed in the brain, with isoform 1 being the longest with a 267 amino acid chain and a weight of approximately 28 kDa. Current studies are being done on several diseases and disorders relating to this gene including lymphoma, systemic lupus erythematosus, anemia, inflammatory bowel disease, leukemia, bronchiolitis, rheumatoid arthritis, hepatitis B, gingivitis, lung cancer and Alzheimer's disease. IL15Ra has also been shown to have interactions with SYK, IL2RB, TRAF2, and AXL in pathways such as the IL-15 signlaing, TCR signaling, and IgA production pathways.

Long Name

Interleukin 15 Receptor alpha

Alternate Names

CD215, IL-15 R alpha, IL-15Ra, IL15 R alpha, IL15RA

Gene Symbol

IL15RA

Additional IL-15R alpha Products

Product Documents for IL-15R alpha Antibody [Janelia Fluor® 646]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IL-15R alpha Antibody [Janelia Fluor® 646]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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