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7 results for "Histamine H4R Small Molecules and Peptides" in Products

Histamine H4R Small Molecules and Peptides

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G protein-coupled receptor superfamily. Histamine H4R is a histamine receptor that is predominantly expressed in hematopoietic cells. Histamine H4R is thought to play a role in inflammation and allergy reponses.

Selective, high affinity H4 agonist

Chemical Name:
5-(2-Aminoethyl)-4-methylimidazole dihydrochloride
Selective, high affinity H4 agonist

H3 antagonist; also H4 inverse agonist

Chemical Name:
N-Cyclohexyl-4-(imidazol-4-yl)-1-piperidinecarbothioamide
Purity:
≥98%
H3 antagonist; also H4 inverse agonist

Standard H3 agonist. Also H4 agonist

Chemical Name:
4-(1H-Imidazol-4-ylmethyl)piperidine dihydrobromide
Standard H3 agonist. Also H4 agonist

Selective H4 antagonist

Chemical Name:
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine
Purity:
≥98%
Selective H4 antagonist

Selective H4 antagonist; orally active

Alternate Names:
VUF 6002
Chemical Name:
1-[(5-Chloro-1H-benzimidazol-2-yl)carbonyl]-4-methylpiperazine maleate
Purity:
≥98%
Selective H4 antagonist; orally active

Potent 5-HT7 agonist

Chemical Name:
(2S)-5-(1,3,5-Trimethylpyrazol-4-yl)-2-(dimethylamino)tetralin
Purity:
≥98%
Potent 5-HT7 agonist

Selective H4 antagonist; orally active

Alternate Names:
VUF 6002
Chemical Name:
1-[(5-Chloro-1H-benzimidazol-2-yl)carbonyl]-4-methylpiperazine maleate
Purity:
≥98%
Selective H4 antagonist; orally active
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