HAX-1: Lysates

HAX-1 (HCLS1-associated protein X-1; also HS1-binding protein1) is a 34-35 kDa intracellular protein with structural similarity to Bcl-2 family proteins. It is ubiquitously expressed, and participates in a variety of cell-specific functions. HAX-1 blocks cardiomyocyte apoptosis via caspase-9 inhibition, downregulates conjugated bile acid secretion via BSEP binding, and via PKD2, transmitts integrin signals to the ER. Human HAX-1 is 279 amino acids (aa) in length and contains two Bcl-2 homology ...