GPR35: Small Molecules and Peptides
GPR35 is a rhodopsin-like G protein-coupled receptor (GPCR). GPR35 isoform B, also known as GPR35B, is longer at the N-terminus, compared to isoform A. Kynurenic acid, a tryptophan metabolite, and 2-acyl lysophosphatidic acid may act as endogenous ligands for GPR35. Human iNKT cells express GPR35 which is functionally active in reducing IL-4 release.
7 results for "GPR35 Small Molecules and Peptides" in Products
7 results for "GPR35 Small Molecules and Peptides" in Products
GPR35: Small Molecules and Peptides
GPR35 is a rhodopsin-like G protein-coupled receptor (GPCR). GPR35 isoform B, also known as GPR35B, is longer at the N-terminus, compared to isoform A. Kynurenic acid, a tryptophan metabolite, and 2-acyl lysophosphatidic acid may act as endogenous ligands for GPR35. Human iNKT cells express GPR35 which is functionally active in reducing IL-4 release.
GPR35 antagonist
| Chemical Name: | 2-Hydroxy-4-[4-(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoylamino]benzoic acid |
| Purity: | ≥98% (HPLC) |
GPR35 agonist
| Chemical Name: | 2-(2-Propyloxyphenyl)-8-azapurin-6-one |
| Purity: | ≥98% (HPLC) |
GPR35 agonist; more potent than zaprinast (Cat. No. 0947)
| Chemical Name: | 4-[[2-[(2-Fluorophenyl)amino]-4-oxo-5(4H)-thiazolylidene]methyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
GPR35 agonist
| Chemical Name: | 2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile |
| Purity: | ≥98% (HPLC) |
GPR35 antagonist
| Chemical Name: | 1-(2,4-Difluorophenyl)-5-[[2-[[(1,1-dimethylehyl)amino]thioxomethyl]hydrazinylidene]methyl]-1H-pyrazole-4-carboxylic acid methyl ester |
| Purity: | ≥98% (HPLC) |
Broad spectrum glutamatergic antagonist
| Chemical Name: | 4-Hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% (HPLC) |
Na+/2Cl-/K+ (NKCC) symporter inhibitor
| Chemical Name: | 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid |
| Purity: | ≥98% (HPLC) |
