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4 results for "Fibroblast Activation Protein alpha/FAP Proteins and Enzymes" in Products

Fibroblast Activation Protein alpha/FAP: Proteins and Enzymes

FAP (also known as seprase) is a transmembrane serine protease, and a soluble and enzymatically active form of FAP known as antiplasmin-cleaving enzyme (APCE) circulates in human plasma. FAP is expressed on reactive stromal fibroblasts in tumor tissue and wound healing and on synoviocytes in rheumatoid arthritis. It exhibits dipeptidyl peptidase activity with substrate specificity similar to DPPIV/CD26, which is specific for N-terminal Xaa-Pro sequences. FAP is also an endopeptidase that can ...

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Analyzed by SEC-MALS

Analyzed by SEC-MALS.

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