12 results for "ErbB2/Her2" in Products
ErbB2/Her2 Products
ErbB2, also called Neu and Her2, is a transmembrane glycoprotein in the ErbB family of tyrosine kinase receptors for EGF superfamily growth factors. ErbB2 is widely expressed in epithelial cells and over-expressed in a large number of breast carcinomas. ErbB2 has no identified ligands but heterodimerizes with ErbB1/EGF R, ErbB3, or ErbB4 to form higher affinity signaling complexes. The protease ADAM10 releases a 110 kDa soluble fragment of ErbB2 from the cell surface. ErbB2 plays roles in ...
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
Negative control for PP 2 (Cat. No. 1407)
Potent and selective dual ErbB2 (HER-2) and EGFR inhibitor
Potent dual EGFR/ErbB2 inhibitor; orally active
Potent ErbB receptor family inhibitor
Potent and selective ErbB2 inhibitor
Potent EGFR and VEGFR inhibitor
Potent irreversible pan ErbB inhibitor
Potent irreversible pan ErbB inhibitor
Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors
Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor
Potent and selective ErbB2 inhibitor
