EGFR Products
EGFR (epidermal growth factor receptor), also known as HER-1, ErbB1, or ErbB, is a transmembrane receptor tyrosine kinase that binds a subset of the EGF family ligands including EGF, Amphiregulin, TGF-alpha, Betacellulin, Epiregulin, HB-EGF, and Epigen. Ligand binding induces EGFR homodimerization as well as heterdimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation, and cell signaling. EGFR can also be recruited to form heterodimers with the ligand-activated ErbB3 or ErbB4.
EGFR signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. EGFR is overexpressed in a wide variety of tumors and is the target of several anti-cancer drugs. Soluble receptors consisting of the extracellular ligand binding domain are generated by alternate splicing in human and mouse.
Products:
2249 results for "EGFR" in Products
2249 results for "EGFR" in Products
EGFR Products
EGFR (epidermal growth factor receptor), also known as HER-1, ErbB1, or ErbB, is a transmembrane receptor tyrosine kinase that binds a subset of the EGF family ligands including EGF, Amphiregulin, TGF-alpha, Betacellulin, Epiregulin, HB-EGF, and Epigen. Ligand binding induces EGFR homodimerization as well as heterdimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation, and cell signaling. EGFR can also be recruited to form heterodimers with the ligand-activated ErbB3 or ErbB4.
EGFR signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. EGFR is overexpressed in a wide variety of tumors and is the target of several anti-cancer drugs. Soluble receptors consisting of the extracellular ligand binding domain are generated by alternate splicing in human and mouse.
Products:
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/9166R |
| Applications: | IHC |
![EGFR Antibody (EGFR/9166R) Immunohistochemistry-Paraffin: EGFR Antibody (EGFR/9166R) [NBP3-23767] -](https://resources.bio-techne.com/images/products/nbp3-23767_rabbit-egfr-mab-egfr-9166r-2412025872339.jpg "Immunohistochemistry-Paraffin: EGFR Antibody (EGFR/9166R) [NBP3-23767] -")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/9166R |
| Applications: | IHC |
![EGFR Antibody (EGFR/9166R) - Azide and BSA Free Immunohistochemistry-Paraffin: EGFR Antibody (EGFR/9166R) - Azide and BSA Free [NBP3-24209] -](https://resources.bio-techne.com/images/products/nbp3-24209_rabbit-egfr-mab-egfr-9166r-azide-and-bsa-free-2412025801636.jpg "Immunohistochemistry-Paraffin: EGFR Antibody (EGFR/9166R) - Azide and BSA Free [NBP3-24209] -")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/9166R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/9166R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/9166R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/9166R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/9166R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/9166R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/9166R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/9166R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #EGFR/8933R |
| Applications: | IHC |
| Source: | NS0 |
| Accession #: | CAA25240.1 |
| Applications: | Bind |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, Flow, IHC, IP, +3 More |
| Sensitivity: | 0.036 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.313 - 20 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Human Milk) |
Human EGFR (Research Grade Cetuximab Biosimilar) Alexa Fluor® 488-conjugated Antibody Best Seller
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Hu1 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Hu1 |
| Applications: | Flow |
