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Dopamine D2 Receptor Agonists: Small Molecules and Peptides

DRD2 encodes the D2 subtype of the dopamine receptor that inhibits adenylyl cyclase activity. Alternative splicing of this G protein-coupled receptor results in two transcript variants encoding different isoforms. DRD2 plays a major role in the neural circuitry that mediates behavioral control, an ability that is essential for adaptive responding and is compromised in a variety of common neuropsychiatric disorders.

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3 results for "Dopamine D2 Receptor Agonists Small Molecules and Peptides" in Products

3 results for "Dopamine D2 Receptor Agonists Small Molecules and Peptides" in Products

Dopamine D2 Receptor Agonists: Small Molecules and Peptides

DRD2 encodes the D2 subtype of the dopamine receptor that inhibits adenylyl cyclase activity. Alternative splicing of this G protein-coupled receptor results in two transcript variants encoding different isoforms. DRD2 plays a major role in the neural circuitry that mediates behavioral control, an ability that is essential for adaptive responding and is compromised in a variety of common neuropsychiatric disorders.

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High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist

Chemical Name: 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
Purity: ≥99% (HPLC)
High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist

D2 and D3 agonist

Alternate Names: N 0923
Chemical Name: (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol hydrochloride
Purity: ≥99% (HPLC)
D2 and D3 agonist

Selective D2 agonist

Chemical Name: (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (2Z)-2-butenedioate
Purity: ≥98% (HPLC)
Selective D2 agonist
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