Rotigotine hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 3896

D2 and D3 agonist
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Key Product Details

Description

D2 and D3 agonist

Alternative Names

N 0923

View all Dopamine D2 Receptor Agonists »

Product Description

Rotigotine hydrochloride is a dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Also has significant affinity for 5-HT1A and adrenergic α2B receptors. Exhibits antiparkinsonian acitivity.

Product Specifications

Molecular Weight

351.93

Formula

C19H25NOS.HCl

Storage

Desiccate at RT

Purity

≥99% (HPLC)

Chemical Name

(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol hydrochloride

CAS Number

125572-93-2

PubChem ID

59226

InChI Key

CEXBONHIOKGWNU-NTISSMGPSA-N

SMILES

CCCN(CCC3=CC=CS3)[C@H]2CCC1=C(O)C=CC=C1C2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 35.19 100

Preparing Stock Solutions for Rotigotine hydrochloride

The following data is based on the product molecular weight 351.93

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.84 mL 14.21 mL 28.41 mL
5 mM 0.57 mL 2.84 mL 5.68 mL
10 mM 0.28 mL 1.42 mL 2.84 mL
50 mM 0.06 mL 0.28 mL 0.57 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Rotigotine hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Rotigotine hydrochloride

For research use only

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