CXCR4 Products
CXCR4, also known as fusin or LESTR, is a G protein-coupled receptor (GPCR) member of the CXC subfamily of chemokine receptors. Human CXCR4 is 352 amino acids (aa) in length with a predicted molecular weight of 40 kDa. The mouse and rat proteins share 91% aa sequence identity with the human protein. CXCR4 is the chemokine receptor for CXCL12. CXCR4 is a critical regulator of progenitor and stem cell mobilization and recruitment during development and during hematopoiesis. As such, antagonists of CXCR4 can be used to harvest hematopoietic stem/progenitor cells from bone marrow. Significantly, CXCR4 also acts as a co-receptor for HIV and mediates viral entry and infection of T cells. Studies on multiple tumor types implicate the CXCL12:CXCR4 axis in tumor metastasis and angiogenesis.
450 results for "CXCR4" in Products
450 results for "CXCR4" in Products
CXCR4 Products
CXCR4, also known as fusin or LESTR, is a G protein-coupled receptor (GPCR) member of the CXC subfamily of chemokine receptors. Human CXCR4 is 352 amino acids (aa) in length with a predicted molecular weight of 40 kDa. The mouse and rat proteins share 91% aa sequence identity with the human protein. CXCR4 is the chemokine receptor for CXCL12. CXCR4 is a critical regulator of progenitor and stem cell mobilization and recruitment during development and during hematopoiesis. As such, antagonists of CXCR4 can be used to harvest hematopoietic stem/progenitor cells from bone marrow. Significantly, CXCR4 also acts as a co-receptor for HIV and mediates viral entry and infection of T cells. Studies on multiple tumor types implicate the CXCL12:CXCR4 axis in tumor metastasis and angiogenesis.
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #44716 |
| Applications: | Flow, IHC, CyTOF-ready, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #247506 |
| Applications: | Flow, IHC, CyTOF-ready, ICC, Neut |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow |
![Immunocytochemistry/ Immunofluorescence: CXCR4 Antibody [NB100-74396]](https://resources.bio-techne.com/images/products/CXCR4-Antibody-Immunocytochemistry-Immunofluorescence-NB100-74396-img0008.jpg "Immunocytochemistry/ Immunofluorescence: CXCR4 Antibody [NB100-74396]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #12G5 |
| Applications: | Flow, CyTOF-reported, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #12G5 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #44717 |
| Applications: | Flow, CyTOF-ready, Neut |
| Reactivity: | Human, Mouse, Rat, Sheep |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Mycoplasma |
![Knockdown Validated: CXCR4 Antibody [NB100-56437]](https://resources.bio-techne.com/images/products/CXCR4-Antibody-Knockdown-Validated-NB100-56437-img0007.jpg "Western Blot: CXCR4 Antibody [NB100-56437]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #44708 |
| Applications: | Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #44717 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat, Monkey, Primate, +3 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: CXCR4 Antibody - BSA Free [NLS1380]](https://resources.bio-techne.com/images/products/CXCR4-Antibody-Immunohistochemistry-Paraffin-NLS1380-img0010.jpg "Immunohistochemistry-Paraffin: CXCR4 Antibody - BSA Free [NLS1380]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
![Western Blot: CXCR4 AntibodyBSA Free [NBP1-77067]](https://resources.bio-techne.com/images/products/CXCR4-Antibody-Western-Blot-NBP1-77067-img0013.jpg "Western Blot: CXCR4 AntibodyBSA Free [NBP1-77067]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #12G5 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat, Sheep |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KO, Mycoplasma |
![Western Blot: CXCR4 AntibodyAzide Free [NBP2-24862]](https://resources.bio-techne.com/images/products/CXCR4-Antibody---Azide-Free-Western-Blot-NBP2-24862-img0004.jpg "Western Blot: CXCR4 AntibodyAzide Free [NBP2-24862]")
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #247506 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #12G5R |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #12G5 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #247506R |
| Applications: | Flow, IHC, CyTOF-ready, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #12G5 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, Mycoplasma |
![Western Blot: CXCR4 AntibodyBSA Free [NBP1-76480]](https://resources.bio-techne.com/images/products/CXCR4-Antibody-Western-Blot-NBP1-76480-img0009.jpg "Western Blot: CXCR4 AntibodyBSA Free [NBP1-76480]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #44717 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #44717 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #247506 |
| Applications: | Flow |
