CD79B: Proteins and Enzymes

CD79B (also known as B29, Ig beta and B cell antigen receptor complex-associated protein beta-chain) is a 37-39 kDa member of the Ig-Superfamily. It is expressed on B cells, and forms a covalent heterodimer with CD79A. This complex interacts noncovalently with membrane Ig, forming the B cell antigen receptor. Within this complex, membrane Ig detects antigen while CD79A/B initiates signaling. CD79B is also required for formation of pre-B cells during B cell development. Mature mouse CD79B is a ...