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CCL2/JE/MCP-1: Simple Plex

CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.

5 results for "CCL2/JE/MCP-1 Simple Plex" in Products

CCL2/JE/MCP-1: Simple Plex

CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.

5 results for "CCL2/JE/MCP-1 Simple Plex" in Products

Simple Plex Cartridge Kit for quantitation of CCL2/MCP-1. Includes wash buffer and sample diluent SD13. For use with the Ella automated immunoassay system.

Simple Plex Cartridge Kit for quantitation of CCL2/JE/MCP-1. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

Catalog #: 894948

Control for use with Human CCL2/JE/MCP-1 Simple Plex Cartridge Kit

Catalog #: 898305

Control for use with Mouse/Rat CCL2/JE/MCP-1 Simple Plex Cartridge Kit

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