Cathepsin B: Small Molecules and Peptides
Cathepsin B is the first described member of the family of lysosomal cysteine proteases. Cathepsin B possesses both endopeptidase and exopeptidase activities, in the latter case acting as a peptidyl-dipeptidase. It is known to process a number of proteins, including pro and active caspases, prorenin and SLPI. Cathepsin B is synthesized as a preproenzyme. Following removal of the signal peptide, the inactive proenzyme undergoes further modifications including removal of the pro region to result in the active enzyme.
2 results for "Cathepsin B Small Molecules and Peptides" in Products
2 results for "Cathepsin B Small Molecules and Peptides" in Products
Cathepsin B: Small Molecules and Peptides
Cathepsin B is the first described member of the family of lysosomal cysteine proteases. Cathepsin B possesses both endopeptidase and exopeptidase activities, in the latter case acting as a peptidyl-dipeptidase. It is known to process a number of proteins, including pro and active caspases, prorenin and SLPI. Cathepsin B is synthesized as a preproenzyme. Following removal of the signal peptide, the inactive proenzyme undergoes further modifications including removal of the pro region to result in the active enzyme.
Selective cathepsin B inhibitor
| Chemical Name: | N-[[(2S,3S)-3-[(Propylamino)carbonyl]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline |
| Purity: | ≥98% (HPLC) |
Potent ATG4B/autophagin-1 inhibitor; also inhibits calpain and cathepsin B
| Chemical Name: | N-[(1S)-2-[(3-Fluoro-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-1-naphthalenecarboxamide |
| Purity: | ≥90% (HPLC) |
