4 results for "Casein Kinase 2 Inhibitors" in Products
Casein Kinase 2 Inhibitors Products
Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinase that is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2 functions as a tetrameric complex consisting of two regulatory β-subunits and two catalytic units (α and α′) in a homomeric or heteromeric conformation.
Whilst the α- and α′-subunits are catalytically identical, proteins that regulate CK2, such ...
Selective cell-permeable CK2 inhibitor
| Alternate Names: | NSC 231634 |
| Chemical Name: | 4,5,6,7-Tetrabromobenzotriazole |
| Purity: | ≥98% (HPLC) |
High affinity, selective CK2 inhibitor
| Chemical Name: | 3-[[5-(4-Methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio]propanoic acid |
| Purity: | ≥98% (HPLC) |
Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2
| Chemical Name: | N-[5-[[3-Cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]propanamide |
| Purity: | ≥98% (HPLC) |
Potent and selective CK2α and CK2α' inhibitor. Also blocks CK2-dependent HIF-1α transcription, causes cell-cycle arrest, induces apoptosis in cancer cells and induces stem cell reprogramming
| Alternate Names: | Silmitasertib |
| Chemical Name: | Sodium 5-[(3-Chlorophenyl)amino]benzo[c]-2,6-naphthyridine-8-carboxylate |
| Purity: | ≥98% (HPLC) |
