BRCA2: Small Molecules and Peptides
BRCA1 and BRCA2 are intracellular proteins that function in the repair of double stranded DNA breaks by homologous recombination and thus function as tumor suppressors. Individuals with heterozygous mutations in either of these genes are at increased risk of breast, ovarian, and other cancers.
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BRCA2: Small Molecules and Peptides
BRCA1 and BRCA2 are intracellular proteins that function in the repair of double stranded DNA breaks by homologous recombination and thus function as tumor suppressors. Individuals with heterozygous mutations in either of these genes are at increased risk of breast, ovarian, and other cancers.
Selective orthosteric inhibitor of the BRCA2-RAD51 interaction
| Chemical Name: | N-(2-((2S,4R)-2-(((S)-1-(2-Chloro-4-methoxyphenyl)ethyl)carbamoyl)-4-hydroxypyrrolidin-1-yl)-2-oxoethyl)-6-fluoroquinoline-2-carboxamide |
| Purity: | ≥98% (HPLC) |