Axin-2: Small Molecules and Peptides
Axin-2, also known as Conductin, is a 95 kDa cytoplasmic protein that inhibits Wnt signaling and promotes epithelial-mesenchymal transition. Axin-2 binds to beta-catenin, glycogen synthase kinase-3 (GSK-3 beta), and the tumor suppressor APC. Loss of Axin-2 function is linked to carcinogenesis as well as abnormal bone and tooth development.
3 results for "Axin-2 Small Molecules and Peptides" in Products
3 results for "Axin-2 Small Molecules and Peptides" in Products
Axin-2: Small Molecules and Peptides
Axin-2, also known as Conductin, is a 95 kDa cytoplasmic protein that inhibits Wnt signaling and promotes epithelial-mesenchymal transition. Axin-2 binds to beta-catenin, glycogen synthase kinase-3 (GSK-3 beta), and the tumor suppressor APC. Loss of Axin-2 function is linked to carcinogenesis as well as abnormal bone and tooth development.
Wnt/β-catenin signaling inhibitor; axin stabilizer
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% (HPLC) |
Wnt pathway inhibitor
| Chemical Name: | 4-[4-(4-Methoxyphenyl)-5-[[[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]thio]-4H-1,2,4-triazol-3-yl]-pyridine |
| Purity: | ≥98% (HPLC) |
endo-IWR 1 synthesized to Ancillary Material Grade
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% |
