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23 results for "additional-transcription-factor-compounds&view=expanded" in Products

Restores mutant p53 activity; proapoptotic

Chemical Name:
1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione
Restores mutant p53 activity; proapoptotic

Core binding factor inhibitor; attenuates hematopoiesis

Alternate Names:
CBF&#946-Runx1 inhibitor II
Chemical Name:
7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one
Purity:
≥98%
Core binding factor inhibitor; attenuates hematopoiesis

Restores mutant p53 activity

Alternate Names:
APR-246
Chemical Name:
2-(Hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one
Purity:
≥98%
Restores mutant p53 activity

Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

Chemical Name:
1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline hydrochloride
Purity:
≥97%
Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

Cryptochrome protein stabilizer; lengthens circadian period

Chemical Name:
N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)methanesulfonamide
Purity:
≥98%
Cryptochrome protein stabilizer; lengthens circadian period

Potent and selective CREB inhibitor

Chemical Name:
3-(3-Aminopropoxy)-N-[2-[[3-[[(4-chloro-2-hydroxyphenyl)amino]carbonyl]-2-naphthalenyl]oxy]ethyl]-2-naphthalenecarboxamide hydrochloride
Purity:
≥98%
Potent and selective CREB inhibitor

Hepatocyte nuclear factor 4α (HNF4α) antagonist

Chemical Name:
2-Methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-1H-benzimidazole
Purity:
≥98%
Hepatocyte nuclear factor 4α (HNF4α) antagonist

Steroid receptor coactivator 3 (SRC-3) inhibitor

Chemical Name:
1-(2-Pyridinyl)ethanone 2-(1-methyl-1H-benzimidazol-2-yl)hydrazone hydrochloride
Purity:
≥98%
Steroid receptor coactivator 3 (SRC-3) inhibitor

Potent and selective Foxo1 inhibitor; orally bioavailable

Chemical Name:
5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Purity:
≥98%
Potent and selective Foxo1 inhibitor; orally bioavailable

p53 inhibitor. Also aryl hydrocarbon receptor agonist

Chemical Name:
1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide
p53 inhibitor. Also aryl hydrocarbon receptor agonist
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