SRPIN340

Tocris Bioscience, part of Bio-Techne | Catalog # 5063

Selective SRPK1 inhibitor
Discontinued Product
5063 has been discontinued. View all Other Kinase Inhibitors products.

Key Product Details

Description

Selective SRPK1 inhibitor

View all Other Kinase Inhibitors »

Product Description

SRPIN340 is a selective serine arginine protein kinase (SRPK) 1 inhibitor (Ki = 0.89 μM). Inhibits SRPK2 at higher concentrations. Does not significantly inhibit other SRPKs such as CLK1 and CLK4, or other classes of SR kinases. Down-regulates expression of VEGF165 but does not affect VEGF165b expression.

Product Specifications

Molecular Weight

349.35

Formula

C18H18F3N3O

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide

CAS Number

218156-96-8

PubChem ID

2797577

InChI Key

DWFGGOFPIISJIT-UHFFFAOYSA-N

SMILES

O=C(C3=CC=NC=C3)NC1=C(N2CCCCC2)C=CC(C(F)(F)F)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 17.47 50
DMSO 34.94 100

Preparing Stock Solutions for SRPIN340

The following data is based on the product molecular weight 349.35

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.86 mL 14.31 mL 28.62 mL
5 mM 0.57 mL 2.86 mL 5.72 mL
10 mM 0.29 mL 1.43 mL 2.86 mL
50 mM 0.06 mL 0.29 mL 0.57 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for SRPIN340

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SRPIN340

For research use only

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