(RS)-MCPG disodium salt

Name: ( RS )-MCPG disodium salt
Brand: Tocris Bioscience
SKU: 3696
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 3696

(1)

Citations (4)

COA / SDS

Non-selective mGlu antagonist; disodium salt of (RS)-MCPG (Cat. No. 0336)

Key Product Details

Description:	Non-selective mGlu antagonist; disodium salt of (RS)-MCPG (Cat. No. 0336)
Chemical Name:	(RS)-α-Methyl-4-carboxyphenylglycine disodium salt
Purity:	≥98% (HPLC)
Molecular Weight:	253.16

View Full Technical Details for (RS)-MCPG disodium salt

Technical Data
Citations / Reviews (1)

Biological Activity for (RS)-MCPG disodium salt

(RS)-MCPG disodium salt is a sodium salt of (RS)-MCPG, a non-selective group I/group II metabotropic glutamate receptor antagonist.

S-enantiomer also available.

Technical Data for (RS)-MCPG disodium salt

M. Wt	253.16
Formula	C₁₀H₉NNa₂O₄
Storage	Store at RT
Purity	≥98% (HPLC)
PubChem ID	90488871
InChi Key	YGOTXTUQJLFNHB-UHFFFAOYSA-L
Smiles	[Na+].[Na+].CC(N)(C([O-])=O)C1=CC=C(C=C1)C([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for (RS)-MCPG disodium salt

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	25.32	100

Preparing Stock Solutions for (RS)-MCPG disodium salt

The following data is based on the product molecular weight 253.16.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.95 mL	19.75 mL	39.50 mL
5 mM	0.79 mL	3.95 mL	7.90 mL
10 mM	0.40 mL	1.98 mL	3.95 mL
50 mM	0.08 mL	0.40 mL	0.79 mL

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Reconstitution Calculator

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References for (RS)-MCPG disodium salt

References are publications that support the biological activity of the product.

Joly Molecular, functional and pharmacological characterization of the metabotropic glutamate receptor Type 5 splice variants: comparison with mGluR1. J.Neurosci. 1995 PMID: 7751958
Eaton Competitive antagonist at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine (CPG) and (RS)-α-methyl-4-carboxyphenylglycine (MCPG). Eur.J.Pharmacol.Mol.Pharmacol.Sect.
Collingridge and Watkins Phenylglycine derivatives as metabotropic glutamate receptor antagonists. TiPS 1994 PMID: 7992387