LF 11
Tocris Bioscience, part of Bio-Techne | Catalog # 4421
Antibiotic; neutralizes LPS
Discontinued Product
4421 has been discontinued.
View all Antibiotics products.
Product Description
LF 11 is a peptide based on the lipopolysaccharide (LPS)-binding region of human lactoferricin. Neutralizes LPS; displays antimicrobial activity against Gram-negative and Gram-positive bacteria. Analog lauryl-LF 11 (Cat. No. 4422) available.Product Specifications
Molecular Weight
1529.81
Formula
C69H112N26O14
Storage
Store at -20°C
CAS Number
832729-13-2
PubChem ID
25089955
InChI Key
SIROSQHTQDVQTI-JDJCIBPGSA-N
SMILES
[H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 2mg/ml in 20% acetonitrile / water |
Calculators
Molarity Calculator
Dilution Calculator
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Background References
References are publications that support the biological activity of the product.
- Japelj Structural origin of endotoxin neutralization and antimicrobial activity of a lactoferrin-based peptide. J.Biol.Chem. 2005 PMID: 15687491
- Andra Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 2005 PMID: 15344905
- Sanchez-Gomez Comparative analysis of selected methods for the assessment of antimicrobial and membrane-permeabilizing activity: a case study for lactoferricin derived peptides. BMC Mirobiol. 2008 PMID: 19014450
Product Specific Notices for LF 11
For research use only
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