Lauryl-LF 11

Name: Lauryl-LF 11
Brand: Tocris Bioscience
SKU: 4422

Tocris Bioscience, part of Bio-Techne | Catalog # 4422

COA / SDS

Analog of LF 11 (Cat. No. 4421); antibiotic

Discontinued Product

4422 has been discontinued. View all Antibiotics products.

Key Product Details

Description:	Analog of LF 11 (Cat. No. 4421); antibiotic
Molecular Weight:	1712.11

View Full Technical Details for Lauryl-LF 11

Technical Data
Citations

Biological Activity for Lauryl-LF 11

Lauryl-LF 11 is a N-terminally acylated analog of LF 11 (Cat. No. 4421). Displays enhanced antibacterial and LPS-binding activities.

Technical Data for Lauryl-LF 11

M. Wt	1712.11
Formula	C₈₁H₁₃₄N₂₆O₁₅
Single Letter Sequence	FQWQRNIRKVR (Modifications: Phe-1 = CH3-(CH2)10-CO-NH-Phe, Arg-11 = C-terminal amide)
Storage	Store at -20°C
CAS Number	832729-14-3
PubChem ID	90488941
InChi Key	AUHGQKBFMDAWAQ-BSHYLFJSSA-N
Smiles	CCCCCCCCCCCNC(CC1CCCCC1)C(O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)CN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Lauryl-LF 11

References are publications that support the biological activity of the product.

Rosenfeld Effect of the hydrophobicity to net positive charge ratio on antibacterial and anti-endotoxin activities of structurally similar antimicrobial peptides. Biochemistry 2010 PMID: 20058937
Andra Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 2005 PMID: 15344905
Zweytick Influence of N-acylation of a peptide derived from human lactoferricin on membrane selectivity. Biochim.Biophys.Acta 2006 PMID: 16616888

Lauryl-LF 11

Tocris Bioscience, part of Bio-Techne | Catalog # 4422

Key Product Details

Biological Activity for Lauryl-LF 11

Technical Data for Lauryl-LF 11

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Lauryl-LF 11

Product Documents for Lauryl-LF 11

COA

Certificate of Analysis

SDS

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