Coenzyme Q10
Tocris Bioscience, part of Bio-Techne | Catalog # 3003
Antioxidant
Discontinued Product
3003 has been discontinued.
View all Additional Antioxidant Compounds products.
Product Description
Coenzyme Q10 is a component of the mitochondrial transporter chain that behaves as a powerful antioxidant. Coenzyme Q10 displays neuroprotective activity. In an animal model of Huntington's disease, Coenzyme Q10 extends survival and delays disease; this effect is more pronounced when combined with Remacemide hydrochloride (Cat. No. 1622). Ferroptosis inhibitor.Product Specifications
Molecular Weight
863.34
Formula
C59H90O4
Storage
Store at -20°C
Purity
≥99% (HPLC)
Chemical Name
2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione
CAS Number
303-98-0
PubChem ID
5281915
InChI Key
ACTIUHUUMQJHFO-UPTCCGCDSA-N
SMILES
O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)=C(C)C1=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| chloroform | 43.17 | 50 | |
| Ethanol | 4.32 | 5 with gentle warming |
Preparing Stock Solutions
for Coenzyme Q10
The following data is based on the product molecular weight 863.34
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 2.32 mL | 11.58 mL | 23.17 mL |
| 2.5 mM | 0.46 mL | 2.32 mL | 4.63 mL |
| 5 mM | 0.23 mL | 1.16 mL | 2.32 mL |
| 25 mM | 0.05 mL | 0.23 mL | 0.46 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Ferrante Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease. J.Neurosci. 2002 PMID: 11880489
- Young Coenzyme Q10: a review of its promise as a neuroprotectant. CNS Spectr. 2007 PMID: 17192765
- Yang and Stockwell Ferroptosis: Death by lipid peroxidation. Trends Cell Biol. 2016 PMID: 26653790
- Shults Coenzyme Q10 in neurodegenerative diseases. Curr.Med.Chem. 2003 PMID: 12871093
Product Specific Notices for Coenzyme Q10
For research use only
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