Cyno Monkey R-Spondin 1 (XP_005543984.1) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3238
Key Product Details
Species
Cynomolgus Monkey
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: R-Spondin 1
R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
Long Name
Roof Plate-specific Spondin 1
Alternate Names
Cristin 3, CRISTIN3, HRspo1, RSPO, RSPO1, RSpondin 1
Gene Symbol
RSPO1
UniProt
Additional R-Spondin 1 Products
Product Documents for Cyno Monkey R-Spondin 1 (XP_005543984.1) VersaClone cDNA
Product Specific Notices for Cyno Monkey R-Spondin 1 (XP_005543984.1) VersaClone cDNA
For research use only
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