R-Spondin 1 Products
R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
202 results for "R-Spondin 1" in Products
202 results for "R-Spondin 1" in Products
R-Spondin 1 Products
R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
| Source: | CHO |
| Accession #: | Q2MKA7 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | NP_619624 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | Q9Z132 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2B Monoclonal Clone #852010 |
| Applications: | B/N |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2B Monoclonal Clone #422407 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | B/N |
![R-Spondin 1 Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/af4645cl1_sheep-r-spondin-1-pab-corafluor-1-12920251455494.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![R-Spondin 1 Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp1-77354cl1_rabbit-r-spondin-1-pab-corafluor-1-892025153290.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
![R-Spondin 1 Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/af3474cl1_goat-r-spondin-1-pab-corafluor-1-109202511303223.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI11A9 |
| Applications: | IHC, WB |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #852010 |
| Applications: | Neut |
| Source: | E. coli |
| Accession #: | Q2MKA7.1 |
| Applications: | BA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Monoclonal Clone #422407 |
| Applications: | WB |
Biotinylated
| Source: | CHO |
| Accession #: | Q2MKA7.1 |
| Applications: | BA |
| Source: | CHO |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2B Monoclonal Clone #852010 |
| Applications: | B/N |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |