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Viral HHV8-ORF74 Alexa Fluor™ Plus 594-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB5264AFP594

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FAB5264AFP594-100UG

Key Product Details

Species Reactivity

Viral

Applications

Flow Cytometry, CyTOF-ready

Label

Alexa Fluor Plus 594 (Excitation = 590 nm, Emission = 618 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 462510

Product Specifications

Immunogen

NS0 mouse myeloma cell line transfected with viral HHV8-ORF74

Specificity

Detects viral HHV8-ORF74.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications

Application
Recommended Usage

CyTOF-ready

Optimal dilution of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilution of this antibody should be experimentally determined.

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: HHV8-ORF74

HHV8‑ORF74 is a 342 amino acid viral 7-transmembrane receptor encoded by the Kaposi's sarcoma-associated herpesvirus 8. The G‑protein-coupled receptor is a constitutively active homologue of CXCR2, the CXCL8 receptor (IL-8 RB). It contributes to Kaposi's sarcoma by triggering expression of paracrine factors such as VEGF-A, inflammatory cytokines, adhesion molecules and chemokines, and enhancing cell growth.

Long Name

Human Herpesvirus 8 ORF74

Alternate Names

HHV8ORF74, KSHV-vGPCR

Entrez Gene IDs

4961460 (Viral)

Gene Symbol

HHV8GK18_GP84

UniProt

Additional HHV8-ORF74 Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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