HHV8-ORF74 Antibody (462510) [Biotin]
Novus Biologicals, part of Bio-Techne | Catalog # FAB5264B
Conjugate
Catalog #
Key Product Details
Species Reactivity
Viral
Applications
Flow Cytometry, CyTOF-ready
Label
Biotin
Antibody Source
Recombinant Monoclonal Mouse IgG2B Clone # 462510
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
NS0 mouse myeloma cell line transfected with viral HHV8-ORF74
Met1-Thr342
Accession # AAB51506
Met1-Thr342
Accession # AAB51506
Specificity
Detects viral HHV8-ORF74.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Description
This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
Applications for HHV8-ORF74 Antibody (462510) [Biotin]
Application
Recommended Usage
CyTOF-ready
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Recommended applications are based on validated applications from the unconjugated base product FAB5264. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: HHV8-ORF74
HHV8-ORF74 is a 342 amino acid viral 7-transmembrane receptor encoded by the Kaposi's sarcoma-associated herpesvirus 8. The G-protein-coupled receptor is a constitutively active homologue of CXCR2, the CXCL8 receptor (IL-8 RB). It contributes to Kaposi's sarcoma by triggering expression of paracrine factors such as VEGF-A, inflammatory cytokines, adhesion molecules and chemokines, and enhancing cell growth.
Long Name
Human Herpesvirus 8 ORF74
Alternate Names
HHV8ORF74, KSHV-vGPCR
Gene Symbol
HHV8GK18_gp84
Additional HHV8-ORF74 Products
Product Documents for HHV8-ORF74 Antibody (462510) [Biotin]
Product Specific Notices for HHV8-ORF74 Antibody (462510) [Biotin]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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