Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

DyLight 594 (Excitation = 593 nm, Emission = 618 nm)

Antibody Source

Polyclonal Sheep IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MyBPC3 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human MyBPC3
Arg1001-Lys1103
Accession # Q14896

Specificity

Detects human MyBPC3 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant mouse MyBPC3 is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for MyBPC3 Antibody [DyLight 594]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MyBPC3

Cardiac myosin binding protein C3 (MyBPC3) is a 140 kDa thick filament-associated protein located in the crossbridge region of cardiac muscle sarcomeres. It is composed of eight Ig-like domains and three fibronectin 3-like domains and is known to be a physiological substrate of cAMP-dependent protein kinase. MyBPC3 has a role in sarcomeric structure and in the regulation of cardiac muscle contraction. MyBPC3 is released into the coronary effluent during myocardial infarction. Mutations in MyBPC3 are associated with hypertrophic cardiomyopathy.

Long Name

Myosin Binding Protein C, Cardiac

Alternate Names

C-protein, cardiac muscle isoform, CMH4, FHC, MYBP-C

Gene Symbol

MYBPC3

Additional MyBPC3 Products

Product Documents for MyBPC3 Antibody [DyLight 594]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MyBPC3 Antibody [DyLight 594]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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