Mouse Neuregulin-3/NRG3 EGF-like Domain Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF753
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Immunogen
Glu284-Pro344
Accession # O35181
Specificity
Clonality
Host
Isotype
Applications for Mouse Neuregulin-3/NRG3 EGF-like Domain Biotinylated Antibody
Western Blot
Sample: Recombinant Mouse Neuregulin-3/NRG3 EGF-like Domain
Formulation, Preparation, and Storage
Purification
Reconstitution
Formulation
Shipping
Stability & Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Neuregulin-3/NRG3
The neuregulin (also known as heregulin) cytokine family is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. The NRG1 gene is the most pleiotropic, encoding more than 14 soluble or transmembrane proteins. NRG1 isoforms can be classified into type I (neu differentiation factor, NDF; heregulin, HRG; acetylcholine receptor inducing activity, ARIA), type II (glial growth factor, GGF) and type III (sensory and motor neuron-derived factor, SMDF) isoforms. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.
Alternate Names
Gene Symbol
UniProt
Additional Neuregulin-3/NRG3 Products
Product Documents for Mouse Neuregulin-3/NRG3 EGF-like Domain Biotinylated Antibody
Product Specific Notices for Mouse Neuregulin-3/NRG3 EGF-like Domain Biotinylated Antibody
For research use only