Detects mouse Glut2. Recognizes mouse Glut2-transfected NS0 cells but not NS0 control transfectants. It also detects Glut2 on mouse insulinoma betaTC-6 cells (1).

Clonality

Monoclonal

Host

Rat

Isotype

IgG_2B

Scientific Data Images for Mouse Glut2 PE-conjugated Antibody

Detection of Glut2 in betaTC‑6 Mouse Cell Line by Flow Cytometry.

betaTC-6 mouse beta cell insulinoma cell line was stained with Rat Anti-Mouse Glut2 PE-conjugated Monoclonal Antibody (Catalog # FAB1440P, filled histogram) or isotype control antibody (Catalog # IC013P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Mouse Glut2 PE-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

0.25-1 µg/10⁶ cells
Sample: betaTC‑6 mouse beta cell insulinoma cell line

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: Glut2

Glut2, also known as SLC2A2, belongs to the facilitative glucose transporter protein family that comprises 13 members. It is an integral membrane glycoprotein with 12 transmembrane domains. Glut2 is expressed predominantly in liver, intestine, kidney and pancreatic beta-cells. It is a low-affinity glucose transporter that has been suggested to function as a glucose sensor in pancreatic beta-cells, and facilitate either glucose uptake or efflux from cells depending on the nutritional state (1, 2).

References

Poitout, V. et al. (1995) Diabetes 44:306.
Olson, A.L. and J.E. Pessin (1996) Annu. Rev. Nut. 16:235.

Long Name

Glucose Transporter Type 2

Alternate Names

SLC2A2

Entrez Gene IDs

6514 (Human); 20526 (Mouse)

Gene Symbol

SLC2A2

UniProt

P14246

Additional Glut2 Products

Product Documents for Mouse Glut2 PE-conjugated Antibody

Product Datasheets

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COA

SDS

Download SDS

Product Specific Notices for Mouse Glut2 PE-conjugated Antibody

For research use only

Citations
Reviews

Spectra Viewer
Flow Cytometry

Mouse Glut2 PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB1440P

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all Glut2 Antibodies »

Product Specifications

Immunogen

Specificity