Mouse FOLR1 Alexa Fluor® 647-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # AF6936R
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Immunohistochemistry, Immunocytochemistry
Label
Alexa Fluor 647 (Excitation = 650 nm, Emission = 668 nm)
Antibody Source
Polyclonal Sheep IgG
Product Specifications
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant mouse FOLR1
Arg23-Ser232
Accession # P35846
Arg23-Ser232
Accession # P35846
Specificity
Detects mouse FOLR1 in direct ELISAs. In direct ELISAs, approximately 30% cross-reactivity with recombinant human FOLR1 is observed.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for Mouse FOLR1 Alexa Fluor® 647-conjugated Antibody
Application
Recommended Usage
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
Background: FOLR1
Folate receptor 1 (FOLR1; also folate receptor alpha and folate binding protein 1/FOLBP1) is a 40-50 kDa member of the folate receptor family. FOLR1 is expressed in reticulocytes, retinal Muller cells and placenta, plus renal, mammary and thymic epithelium, where it mediates the transport of 5-methyltetrahydrofolate into the cell. The mouse FOLR1 preproprecursor is 255 amino acid (aa) in length. It contains a GPI-linked glycoprotein that is 208 aa in size (aa 25-232), and which possesses three potential N-linked glycosylation sites. There is one potential isoform variant that shows a 105 aa substitution for aa 110-255. Over aa 23-232, mouse FOLR1 shares 83% and 93% aa sequence identity with human and rat FOLR1, respectively.
Long Name
Folate Receptor 1
Alternate Names
FBP, Folbp1, FR-alpha, MOv18
Gene Symbol
FOLR1
UniProt
Additional FOLR1 Products
Product Specific Notices for Mouse FOLR1 Alexa Fluor® 647-conjugated Antibody
This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.
For research use only
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