MDGA1 Antibody [PE]
Novus Biologicals, part of Bio-Techne | Catalog # AF5055P
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
PE (Excitation = 488 nm, Emission = 575 nm)
Antibody Source
Polyclonal Sheep IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human MDGA1
Gln19-Gly931
Accession # Q8NFP4
Gln19-Gly931
Accession # Q8NFP4
Specificity
Detects human MDGA1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human MDGA2 is observed.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for MDGA1 Antibody [PE]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: MDGA1
MDGA-1 (MAM domain-containing GPI anchor protein 1) is a 135-140 kDa, novel member of the Ig-superfamily. It is expressed on embryonic neurons destined for cortical layers 2/3, as well as migrating basilar pontine neurons and D1 interneurons of the spinal cord. Human proMDGA-1 is 937 amino acids (aa) in length (SwissProt #:Q8NFP4). It is a GPI-linked glycoprotein that contains six consecutive Ig-like domains (aa #24-631), followed by one fibronectin type III domain (aa #640-739), a MAM region (aa #751-918), and a cleavable propeptide (aa #933-955). There are at least three potential variants. One shows a 48 aa substitution for aa #936-955, a second shows a 58 aa substitution for aa #847-955, and a third shows a 51 aa substitution for aa #537-955. Over aa #19-931, human MDGA-1 is 95% aa identical to mouse MDGA-1.
Long Name
MAM Domain Containing Glycosylphosphatidylinositol Anchor 1
Alternate Names
GPIM, MAMDC3
Gene Symbol
MDGA1
Additional MDGA1 Products
Product Documents for MDGA1 Antibody [PE]
Product Specific Notices for MDGA1 Antibody [PE]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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