Human CMG-2/ANTXR2 Alexa Fluor™ Plus 647-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB29401AFP647
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
ELISA
Label
Alexa Fluor Plus 647 (Excitation = 658 nm, Emission = 675 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # 406510
Product Specifications
Specificity
Detects human CMG-2/ANTXR2 in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications
Application
Recommended Usage
ELISA
Optimal dilution of this antibody should be experimentally determined.
Background: CMG-2/ANTXR2
Capillary Morphogenesis Protein 2 (CMG-2) is an anthrax toxin receptor (ATR) family protein that contains a von Willebrand factor type A domain. As a result of alternative splicing, at least four isoforms of secreted or type I membrane proteins exist. CMG-2 is widely expressed in human tissues. It binds selectively to collagen type IV and laminin and is also capable of binding the protective antigen (PA) of Bacillus Anthracis in a divalent cation-dependent manner. Soluble CMG-2 is a potent antitoxin and may be used as a treatment of anthrax. Within the region used as immunogen, human and mouse CMG-2 share 76% amino acid sequence homology.
Long Name
Capillary Morphogenesis Protein 2
Alternate Names
ANTXR2, cI-35, CMG2, ISH, JHS
Gene Symbol
ANTXR2
UniProt
Additional CMG-2/ANTXR2 Products
Product Specific Notices
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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