Muscarinic receptors are widely distributed throughout the body and control distinct functions according to location and subtype (M1 - M5). They are predominantly expressed in the parasympathetic nervous system where they exert both inhibitory and excitatory effects. Stimulation of CHRM5 is known to increase cyclic AMP levels. The clinical implications of CHRM5 are unknown but it may be linked to schizophrenia.

Long Name

Cholinergic Receptor Muscarinic 5

Alternate Names

HM5, M5, M5R, mAChR M5

Entrez Gene IDs

1133 (Human); 213788 (Mouse); 53949 (Rat)

Gene Symbol

CHRM5

UniProt

P08912

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Product Specific Notices for Human CHRM5 Alexa Fluor™ Plus 647-conjugated Antibody

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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Human CHRM5 Alexa Fluor™ Plus 647-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB10323AFP647

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

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Product Specifications

Specificity

Clonality

Host

Isotype

Applications for Human CHRM5 Alexa Fluor™ Plus 647-conjugated Antibody

CyTOF-ready

Flow Cytometry

Background: CHRM5