HAX1 is encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

HCLS1 associated protein X-1

Alternate Names

HAX1, HCLSBP1, HS1BP1, SCN3

Gene Symbol

HAX1

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Product Documents for HAX-1 Antibody [Janelia Fluor® 669]

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Product Specific Notices for HAX-1 Antibody [Janelia Fluor® 669]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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HAX-1 Antibody [Janelia Fluor® 669]

Novus Biologicals, part of Bio-Techne | Catalog # AF5458JF669

Key Product Details

Species Reactivity

Applications

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Product Specifications

Immunogen

Specificity

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Host

Isotype

Applications for HAX-1 Antibody [Janelia Fluor® 669]

Immunocytochemistry

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

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Concentration

Shipping

Stability & Storage

Background: HAX-1