Chorionic Gonadotropin beta Chain (hCG beta) Antibody (HCGb/54+ HCGb/459) [CoraFluor™ 1]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34632CL1
![Chorionic Gonadotropin beta Chain (hCG beta) Antibody (HCGb/54+ HCGb/459) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp2-34632cl1_mouse-hcg-beta-mab-hcgb-54-hcgb-459-cl1-810202512262816.png "Product Feature: CoraFluor Probes for TR-FRET")
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
CoraFluor 1
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # HCGb/54+ HCGb/459
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Recombinant Chorionic Gonadotropin beta Chain (hCG beta) protein (HCGb/54 and HCGb/459) (Uniprot: P01233)
Localization
Cytoplasmic, secreted
Specificity
This monoclonal antibody reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Marker
Pregnancy & Choriocarcinoma Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Description
This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
Scientific Data Images
Product Feature: CoraFluor Probes for TR-FRET
CoraFluor™ 1, amine reactive (Catalog:7920) and CoraFluor™ 2, amine reactive (Catalog # 7950) are terbium-based probes that have been developed for use as TR-FRET donors. They emit wavelengths compatible with commonly used fluorescent acceptor dyes such as BODIPY® (or BDY) and Janelia Fluor® dyes, FITC (Catalog # 5440), TMR and Cyanine 5 (Catalog # 5436). CoraFluor™ fluorescence is brighter and more stable in biological media than existing TR-FRET donors, leading to enhanced sensitivity and improved data generation. CoraFluor™ 1 exhibits excitation upon exposure to a 337 nm UV laser.Applications
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Recommended applications are based on validated applications from the unconjugated base product NBP2-34632. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
PBS
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark. Do not freeze.
Background: Chorionic Gonadotropin beta Chain (HCG beta)
Long Name
Chorionic Gonadotropin beta Chain
Alternate Names
CG-Beta, CGB, CGB3, CGB5, CGB8, Choriogonadotropin Subunit Beta
Gene Symbol
CGB3
Additional Chorionic Gonadotropin beta Chain (HCG beta) Products
- All Products for Chorionic Gonadotropin beta Chain (HCG beta)
- Chorionic Gonadotropin beta Chain (HCG beta) ELISA Kits
- Chorionic Gonadotropin beta Chain (HCG beta) Primary Antibodies
- Chorionic Gonadotropin beta Chain (HCG beta) Proteins and Enzymes
- Chorionic Gonadotropin beta Chain (HCG beta) Simple Plex
Product Specific Notices
Sold for research purposes only under agreement from Massachusetts General Hospital, US Patent No. 12,134,721. A license is required for development of new commercial assay platforms (e.g., microarrays, microfluidics), diagnostic use or other unlicensed uses. Please contact Technical Support for further details: techsupport@bio-techne.com.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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