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4 results for "V1b Vasopressin R/AVPR1B Small Molecules and Peptides" in Products
V1b Vasopressin R/AVPR1B Small Molecules and Peptides
AVPR1B acts as a receptor for arginine vasopressin. AVPR1B belongs to the subfamily of G protein-coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. AVPR1B is primarily located in the anterior pituitary, where it stimulates ACTH release. AVPR1B is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome.
Alternate Names:
Nelivaptan
Chemical Name:
(2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide
Purity:
≥98%
Alternate Names:
AVP
Purity:
≥95%
Chemical Name:
2-(3-Chloro-4-fluorophenyl)-N-(1-methylethyl)-6-[3-(4-morpholinyl)propoxy]-4-oxo-pyrido[2,3-d]pyrimidine-3(4H)-acetamide hydrochloride
Purity:
≥98%
