Desmopressin
Tocris Bioscience, part of Bio-Techne | Catalog # 3396
Synthetic vasopressin analog; V1B and V2 agonist
Key Product Details
Description
Synthetic vasopressin analog; V1B and V2 agonist
Product Description
Desmopressin is a synthetic vasopressin analog that acts as an agonist at V1B and V2 receptors (EC50 values are 11.4 and 23.9 nM and Ki values are 5.84 and 65.9 nM respectively). Prevents polycystic kidney disease formation and exhibits antidiuretic, antiproliferative, hemostatic and hypotensive activity in vivo.Product Specifications
Molecular Weight
1069.22
Formula
C46H64N14O12S2
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
16679-58-6
PubChem ID
5311065
InChI Key
NFLWUMRGJYTJIN-PNIOQBSNSA-N
SMILES
NC(=O)CC[C@@H]1NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@H](CCCNC(N)=N)C(=O)NCC(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 4mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
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Background References
References are publications that support the biological activity of the product.
- Gomez Desmopressin and other synthetic vasopressin analogues in cancer treatment. Bull.Cancer 2006 PMID: 16517412
- Torres Vasopressin antagonists in polycystic kidney disease. Semin.Nephrol. 2008 PMID: 18519091
- Saito 1-Desamino-8-D-arginine vasopressin (DDAVP) as an agonist on V1b vasopressin receptor. Biochem.Pharmacol. 1997 PMID: 9264324
Product Specific Notices for Desmopressin
For research use only
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