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83 results for "UNC5H2/UNC5B" in Products

UNC5H2/UNC5B Products

UNC5H2/UNC5B is a transmembrane molecule that mediates axon repulsion and growth cone collapse through interactions with Netrin, Neogenin, and FLRT3. Its association with DCC switches the DCC-Netrin-1 response from attraction to repulsion. Outside the nervous system, UNC5H2 facilitates Netrin-1-mediated inhibition of capillary branching and leukocyte migration as well as Netrin-1-mediated promotion of osteoclast differentiation. It is downregulated in multiple cancers and inhibits tumor cell growth and invasion. It also plays a critical role in the development of atherosclerosis and the survival of renal tubular epithelial cells during acute kidney injury.

Reactivity: Human, Mouse
Details: Mouse IgG2B Monoclonal Clone #Guido-1
Applications: Flow
Novus Antibodies
Source: NS0
Accession #: O08722
Applications: Bind
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Rat
Details: Mouse IgG2a Monoclonal Clone #187305
Reactivity: Rat
Details: Mouse IgG2a Monoclonal Clone #187305
Reactivity: Rat
Details: Mouse IgG2a Monoclonal Clone #187305
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