UNC5H2/UNC5B Products
UNC5H2/UNC5B is a transmembrane molecule that mediates axon repulsion and growth cone collapse through interactions with Netrin, Neogenin, and FLRT3. Its association with DCC switches the DCC-Netrin-1 response from attraction to repulsion.
Outside the nervous system, UNC5H2 facilitates Netrin-1-mediated inhibition of capillary branching and leukocyte migration as well as Netrin-1-mediated promotion of osteoclast differentiation. It is downregulated in multiple cancers and inhibits tumor cell growth and invasion. It also plays a critical role in the development of atherosclerosis and the survival of renal tubular epithelial cells during acute kidney injury.
Products:
71 results for "UNC5H2/UNC5B" in Products
71 results for "UNC5H2/UNC5B" in Products
UNC5H2/UNC5B Products
UNC5H2/UNC5B is a transmembrane molecule that mediates axon repulsion and growth cone collapse through interactions with Netrin, Neogenin, and FLRT3. Its association with DCC switches the DCC-Netrin-1 response from attraction to repulsion.
Outside the nervous system, UNC5H2 facilitates Netrin-1-mediated inhibition of capillary branching and leukocyte migration as well as Netrin-1-mediated promotion of osteoclast differentiation. It is downregulated in multiple cancers and inhibits tumor cell growth and invasion. It also plays a critical role in the development of atherosclerosis and the survival of renal tubular epithelial cells during acute kidney injury.
Products:
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Rat |
| Details: | Mouse IgG2a Monoclonal Clone #187305 |
| Applications: | WB |
| Source: | NS0 |
| Accession #: | O08722 |
| Applications: | Bind |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Rat |
| Details: | Mouse IgG2a Monoclonal Clone #187305 |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Mouse IgG2a Monoclonal Clone #187305 |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Mouse IgG2a Monoclonal Clone #187305 |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Mouse IgG2a Monoclonal Clone #187305 |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Mouse IgG2a Monoclonal Clone #187305 |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Mouse IgG2a Monoclonal Clone #187305 |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Mouse IgG2a Monoclonal Clone #187305 |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Mouse IgG2a Monoclonal Clone #187305 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: UNC5H2/UNC5B Antibody [NBP3-17778]](https://resources.bio-techne.com/images/products/UNC5H2-UNC5B-Antibody-Immunohistochemistry-Paraffin-NBP3-17778-img0001.jpg "Immunohistochemistry-Paraffin: UNC5H2/UNC5B Antibody [NBP3-17778]")
| Reactivity: | Human, Mouse, Rat, Canine, Bovine |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1A9 |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: UNC5H2/UNC5B Antibody [NBP2-42523]](https://resources.bio-techne.com/images/products/UNC5H2-UNC5B-Antibody-Western-Blot-NBP2-42523-img0001.jpg "Western Blot: UNC5H2/UNC5B Antibody [NBP2-42523]")