51 results for "Topoisomerase I" in Products
Topoisomerase I Products
Topoisomerases are nuclear enzymes involved in a variety of cellular activities such as chromosome condensation, DNA replication, transcription, recombination and segregation at mitosis. Human topoisomerase I is a 100kD protein capable of relaxing positively and negatively supercoiled DNA by performing a transient single stranded nick which is then religated at the end of the reaction. It has been shown that the enzyme is located in regions of the genome that are undergoing active RNA ...
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Func |
![Topoisomerase I Antibody - BSA Free Immunocytochemistry/ Immunofluorescence: Topoisomerase I Antibody - BSA Free [NBP1-90365]](https://resources.bio-techne.com/images/products/nbp1-90365_rabbit-polyclonal-topoisomerase-i-antibody-295202516264514.jpg "Immunocytochemistry/ Immunofluorescence: Topoisomerase I Antibody - BSA Free [NBP1-90365]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #3D4W6 |
| Applications: | IHC, WB, ELISA, ICC/IF, IP |
![Western Blot: Topoisomerase I Antibody (3D4W6) [NBP3-15450]](https://resources.bio-techne.com/images/products/Topoisomerase-I-Antibody-3D4W6-Western-Blot-NBP3-15450-img0006.jpg "Western Blot: Topoisomerase I Antibody (3D4W6) [NBP3-15450]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #6D8 |
| Applications: | IHC, WB, ELISA, Flow, IP |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1A1 |
| Applications: | IHC, WB, ELISA |
![Western Blot: Topoisomerase I Antibody (1A1) [H00007150-M01]](https://resources.bio-techne.com/images/products/Topoisomerase-I-Antibody-1A1-Western-Blot-H00007150-M01-img0014.jpg "Western Blot: Topoisomerase I Antibody (1A1) [H00007150-M01]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, IP |
![Western Blot: Topoisomerase I Antibody [NBP1-30482]](https://resources.bio-techne.com/images/products/Topoisomerase-I-Antibody-Western-Blot-NBP1-30482-img0011.jpg "Western Blot: Topoisomerase I Antibody [NBP1-30482]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: Topoisomerase I Antibody [NBP1-30481]](https://resources.bio-techne.com/images/products/Topoisomerase-I-Antibody-Western-Blot-NBP1-30481-img0002.jpg "Western Blot: Topoisomerase I Antibody [NBP1-30481]")
| Applications: | ELISA |
| Applications: | WB, ELISA, MA, AP |
Catalog #:
NBP1-90365PEP
| Applications: | AC |
| Applications: | ELISA |
| Applications: | WB |
![Western Blot: Topoisomerase I Overexpression Lysate [NBL1-17194]](https://resources.bio-techne.com/images/products/Topoisomerase-I-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-17194-img0002.jpg "Western Blot: Topoisomerase I Overexpression Lysate [NBL1-17194]")
Catalog #:
NBP1-30482AFP555
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
Catalog #:
NBP1-30482AFP680
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Topoisomerase I Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp1-30482cl1_rabbit-topoisomerase-i-pab-corafluor-1-10920251258322.png "Product Feature: CoraFluor Probes for TR-FRET")
Catalog #:
NBP1-30482AFP594
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
Catalog #:
NBP1-30482AFP488
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
Catalog #:
NBP1-30482AFP647
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
Catalog #:
NBP1-30482AFP405
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
DNA topoisomerase I inhibitor; antitumor
| Alternate Names: | Irinotecan,Camptothecin 11 |
| Chemical Name: | (4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylic acid ester hydrochloride |
| Purity: | ≥98% (HPLC) |
DNA topoisomerase I inhibitor; antitumor
| Alternate Names: | 7-Ethyl-10-hydroxycamptothecin |
| Chemical Name: | (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione |
| Purity: | ≥98% (HPLC) |
DNA topoisomerase inhibitor
| Chemical Name: | (S)-4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |